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Sertraline
Drug ClassSSRI
Year Approved1991
Conditions TreatedDepression, anxiety, PTSD
AvailabilityPrescription
About Sertraline
An SSRI antidepressant marketed as Zoloft. Sertraline treats depression, anxiety disorders, PTSD, and OCD. It is among the most prescribed antidepressants in the US. Sertraline is generally well tolerated and effective across a broad range of conditions. It is also approved for panic disorder and social anxiety disorder. Common side effects include nausea, insomnia, and sexual dysfunction. Sertraline has become the default first choice antidepressant for many clinicians due to its safety and efficacy profile.