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Acetaminophen
About Acetaminophen
Also known as paracetamol outside the US, acetaminophen is one of the most used medications in the world. It treats pain and fever but not inflammation. Acetaminophen works through a poorly understood mechanism possibly involving COX 3 or endocannabinoid reuptake. Unlike NSAIDs, it does not cause stomach irritation. Overdose causes severe liver damage and is the leading cause of acute liver failure in the US. The antidote N acetylcysteine is effective if given promptly.
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