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Brexpiprazole

Antipsychotic2015
Drug ClassAntipsychotic
Year Approved2015
Conditions TreatedSchizophrenia, depression
AvailabilityPrescription

About Brexpiprazole

A serotonin dopamine activity modulator marketed as Rexulti. Brexpiprazole treats schizophrenia and is used as an adjunct for major depressive disorder. It is a partial agonist at dopamine and serotonin receptors, similar to aripiprazole but designed to reduce restlessness. Brexpiprazole has a more favorable tolerability profile than older antipsychotics. Dosing differs between its depression and schizophrenia indications. The drug represents refinement of partial agonist antipsychotic design.

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