Not medical advice. This site is general information only. In an emergency call your local emergency number. For advice about your own health, speak to a doctor, pharmacist or other qualified health professional.
Cyclosporine
About Cyclosporine
A calcineurin inhibitor that revolutionized organ transplantation. Cyclosporine or Sandimmune prevents organ rejection by suppressing T cell activation. Discovered in a soil sample from Norway in 1969, cyclosporine dramatically improved transplant survival rates. After its introduction, one year kidney graft survival rose substantially. The drug can cause kidney damage, high blood pressure, and increased infection risk. It is also used for psoriasis and other autoimmune conditions.
Related Medications
Tacrolimus
A calcineurin inhibitor more potent than cyclosporine. Tacrolimus or Prograf prevents organ transplant rejecti...
Mycophenolate
An immunosuppressant that inhibits purine synthesis in lymphocytes. Mycophenolate or CellCept prevents organ t...
Azathioprine
One of the first immunosuppressants for organ transplantation. Azathioprine or Imuran prevents organ rejection...
Methotrexate
A versatile medication used in oncology, rheumatology, and dermatology. Methotrexate treats certain cancers, r...