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Rituximab

Monoclonal Antibody1997
Drug ClassMonoclonal Antibody
Year Approved1997
Conditions TreatedLymphoma, rheumatoid arthritis
AvailabilityPrescription

About Rituximab

The first monoclonal antibody approved for cancer treatment. Rituximab or Rituxan targets CD20, a protein on B lymphocytes. It treats non Hodgkin lymphoma and rheumatoid arthritis. Rituximab was a breakthrough in targeted cancer therapy, demonstrating that antibodies could treat cancer. The drug depletes B cells, which can increase infection risk. Rituximab is also used for autoimmune conditions including multiple sclerosis. It remains one of the most widely used and successful cancer biologics.

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