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Topiramate

Anticonvulsant1996
Drug ClassAnticonvulsant
Year Approved1996
Conditions TreatedSeizures, migraine
AvailabilityPrescription

About Topiramate

An antiseizure medication also approved for migraine prevention. Topiramate or Topamax treats partial seizures, generalized seizures, and migraine. It works through multiple mechanisms including sodium channel blockade and GABA enhancement. Topiramate can cause weight loss, making it attractive for some patients. Cognitive side effects including word finding difficulty and memory problems are common. The drug is also approved for weight loss in combination with phentermine as Qsymia.

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