Not medical advice. This site is general information only. In an emergency call your local emergency number. For advice about your own health, speak to a doctor, pharmacist or other qualified health professional.

Mid 20th Century

65 medications

Amoxicillin

Antibiotic1972

A semisynthetic penicillin antibiotic that is widely prescribed for children and adults. Amoxicillin is absorb...

Doxycycline

Antibiotic1967

A tetracycline antibiotic used for a remarkably wide range of conditions. Doxycycline treats acne, Lyme diseas...

Metronidazole

Antibiotic1960

An antibiotic effective against anaerobic bacteria and certain parasites. Metronidazole treats bacterial vagin...

Cephalexin

Antibiotic1971

A first generation cephalosporin antibiotic commonly prescribed for skin infections, strep throat, and urinary...

Clindamycin

Antibiotic1966

A lincosamide antibiotic effective against anaerobic bacteria. Clindamycin treats skin infections, dental absc...

Sulfamethoxazole-Trimethoprim

Antibiotic1973

A combination antibiotic also known as Bactrim or Septra. Sulfamethoxazole and trimethoprim work synergistical...

Vancomycin

Antibiotic1958

A powerful glycopeptide antibiotic reserved for severe infections including MRSA. Vancomycin was originally de...

Erythromycin

Antibiotic1952

A macrolide antibiotic discovered in a soil sample from the Philippines. Erythromycin was the first macrolide,...

Gentamicin

Antibiotic1963

An aminoglycoside antibiotic used for serious gram negative infections and sepsis. Gentamicin is derived from ...

Tetracycline

Antibiotic1953

A broad spectrum antibiotic originally derived from Streptomyces bacteria. Tetracycline treats acne, respirato...

Nitrofurantoin

Antibiotic1953

A urinary tract antiseptic specifically used for uncomplicated bladder infections. Nitrofurantoin concentrates...

Isoniazid

Antibiotic1952

A first line tuberculosis medication that kills actively dividing TB bacteria. Isoniazid is used for both acti...

Rifampin

Antibiotic1971

A key tuberculosis drug that kills both dividing and dormant TB bacteria. Rifampin is derived from Amycolatops...

Ibuprofen

NSAID1969

A nonsteroidal anti inflammatory drug developed by Boots Group in England. Ibuprofen treats headaches, muscle ...

Acetaminophen

Analgesic1955

Also known as paracetamol outside the US, acetaminophen is one of the most used medications in the world. It t...

Naproxen

NSAID1976

A longer acting NSAID whose long half life permits less frequent dosing than short acting NSAIDs. Naproxen tre...

Diclofenac

NSAID1973

A potent NSAID widely used outside the US for arthritis and pain. Diclofenac treats osteoarthritis, rheumatoid...

Fentanyl

Opioid1960

A synthetic opioid roughly 50 to 100 times more potent than morphine. Fentanyl treats breakthrough cancer pain...

Tramadol

Opioid1977

A synthetic opioid with dual action: it binds to opioid receptors and inhibits serotonin and norepinephrine re...

Naloxone

Opioid Antagonist1971

A life saving medication that reverses opioid overdoses. Naloxone or Narcan displaces opioids from receptors, ...

Metoprolol

Beta Blocker1978

A cardioselective beta 1 blocker widely prescribed for cardiovascular conditions. Metoprolol treats high blood...

Furosemide

Diuretic1964

A loop diuretic that removes excess fluid from the body. Furosemide or Lasix treats heart failure, kidney dise...

Hydrochlorothiazide

Diuretic1959

A thiazide diuretic that is one of the most prescribed blood pressure medications. Hydrochlorothiazide treats ...

Spironolactone

Diuretic1960

A potassium sparing diuretic that blocks aldosterone receptors. Spironolactone treats heart failure, high bloo...

Warfarin

Anticoagulant1954

The most widely used oral anticoagulant for decades. Warfarin or Coumadin prevents blood clots by inhibiting v...

Polio Vaccine

Vaccine1955

Developed by Jonas Salk and licensed in 1955, the injected polio vaccine uses killed virus. Albert Sabin later...

MMR Vaccine

Vaccine1971

A combined vaccine protecting against measles, mumps, and rubella. The MMR vaccine was developed by Maurice Hi...

Pneumococcal Vaccine

Vaccine1977

A vaccine against Streptococcus pneumoniae bacteria, which cause pneumonia, meningitis, and blood infections. ...

Meningococcal Vaccine

Vaccine1978

A vaccine against Neisseria meningitidis, a bacteria that causes meningitis and blood infections. Meningococca...

Diazepam

Benzodiazepine1963

A benzodiazepine discovered by Leo Sternbach at Hoffmann La Roche. Diazepam or Valium was the top selling drug...

Lithium

Mood Stabilizer1970

A simple element that remains the gold standard treatment for bipolar disorder. Lithium treats mania and preve...

Methylphenidate

Stimulant1955

A central nervous system stimulant marketed as Ritalin. Methylphenidate treats ADHD by increasing dopamine and...

Loperamide

Antidiarrheal1976

An opioid receptor agonist that does not cross the blood brain barrier. Loperamide or Imodium treats diarrhea ...

Levothyroxine

Thyroid Hormone1950

A synthetic thyroid hormone that replaces the natural hormone T4. Levothyroxine or Synthroid treats hypothyroi...

Prednisone

Corticosteroid1955

A synthetic corticosteroid that mimics cortisol. Prednisone treats a vast range of inflammatory and autoimmune...

Hydrocortisone

Corticosteroid1952

A corticosteroid identical to natural cortisol. Hydrocortisone or Cortef treats adrenal insufficiency includin...

Estradiol

Estrogen1975

The primary female estrogen hormone. Estradiol treats menopausal symptoms including hot flashes, night sweats,...

Clomiphene

Fertility Drug1967

A fertility medication that stimulates ovulation. Clomiphene or Clomid treats infertility in women who do not ...

Clemastine

Antihistamine1967

A first generation antihistamine with anticholinergic properties. Clemastine or Tavist treats allergic rhiniti...

Ketamine

Anesthetic1970

A unique anesthetic that produces dissociative anesthesia. Ketamine or Ketalar maintains blood pressure and br...

Isoflurane

Anesthetic1979

An inhaled general anesthetic. Isoflurane or Forane is a halogenated ether that maintains general anesthesia. ...

Valproic Acid

Anticonvulsant1967

A broad spectrum antiseizure medication also used for bipolar disorder and migraine prevention. Valproic acid ...

Carbamazepine

Anticonvulsant1963

A first line medication for partial seizures and trigeminal neuralgia. Carbamazepine or Tegretol treats seizur...

Azathioprine

Immunosuppressant1968

One of the first immunosuppressants for organ transplantation. Azathioprine or Imuran prevents organ rejection...

Methotrexate

Immunosuppressant1953

A versatile medication used in oncology, rheumatology, and dermatology. Methotrexate treats certain cancers, r...

Cisplatin

Chemotherapy1978

A platinum based chemotherapy drug. Cisplatin or Platinol treats testicular, bladder, ovarian, and lung cancer...

Cyclophosphamide

Chemotherapy1959

A widely used chemotherapy drug. Cyclophosphamide or Cytoxan treats lymphoma, leukemia, breast cancer, and aut...

Doxorubicin

Chemotherapy1974

A powerful chemotherapy drug in the anthracycline class. Doxorubicin or Adriamycin treats breast cancer, lymph...

Tamoxifen

Hormone Therapy1977

A selective estrogen receptor modulator or SERM. Tamoxifen or Nolvadex treats estrogen receptor positive breas...

Vincristine

Chemotherapy1963

A chemotherapy drug derived from the Madagascar periwinkle plant. Vincristine or Oncovin treats acute lymphobl...

Fluorouracil

Chemotherapy1962

A chemotherapy drug that inhibits DNA synthesis. Fluorouracil or 5 FU treats colon cancer, breast cancer, and ...

Timolol

Beta Blocker1978

A beta blocker eye drop that lowers intraocular pressure. Timolol or Timoptic was the first beta blocker appro...

Allopurinol

Urate Lowering1966

A medication that lowers uric acid levels. Allopurinol or Zyloprim treats gout and prevents kidney stones in p...

Colchicine

Anti-inflammatory1961

One of the oldest medications still in use, derived from the autumn crocus plant. Colchicine treats acute gout...

Hydroxychloroquine

Antimalarial1955

A medication originally developed for malaria that is now mainly used for autoimmune diseases. Hydroxychloroqu...

Deferoxamine

Chelating Agent1968

A medication that binds excess iron and removes it from the body. Deferoxamine or Desferal treats iron poisoni...

Ampicillin

Antibiotic1961

A broad spectrum penicillin that treats a wide range of bacterial infections. Ampicillin treats meningitis, en...

Indomethacin

NSAID1965

One of the most potent NSAIDs, discovered in 1963. Indomethacin or Indocin treats acute gout, ankylosing spond...

Sulindac

NSAID1978

An NSAID prodrug that may have less kidney toxicity than other NSAIDs. Sulindac or Clinoril treats osteoarthri...

Niacin

Vitamin B31955

A B vitamin that at pharmacological doses lowers cholesterol. Niacin or nicotinic acid lowers LDL cholesterol ...

Fosfomycin

Antibiotic1969

A unique antibiotic notable for very short treatment regimens for uncomplicated bladder infections. Fosfomycin...

Bromocriptine

Dopamine Agonist1978

A dopamine receptor agonist derived from ergot fungus. Bromocriptine or Parlodel treats prolactinomas, pituita...

Amphotericin B

Antifungal1958

A powerful antifungal known as amphotericin or by its nickname Ampho-terrible due to severe side effects. Amph...

Clotrimazole

Antifungal1972

An imidazole antifungal available over the counter. Clotrimazole or Lotrimin treats vaginal yeast infections, ...

Simethicone

Antiflatulent1960

A medication that relieves intestinal gas and bloating. Simethicone or Gas-X works by breaking up gas bubbles ...