Not medical advice. This site is general information only. In an emergency call your local emergency number. For advice about your own health, speak to a doctor, pharmacist or other qualified health professional.

Late 20th Century

91 medications

Azithromycin

Antibiotic1981

A macrolide antibiotic with a long half life that permits infrequent dosing and short treatment courses. The Z...

Ciprofloxacin

Antibiotic1987

A fluoroquinolone antibiotic with broad spectrum activity. Ciprofloxacin gained fame during the 2001 anthrax a...

Celecoxib

NSAID1999

A selective COX 2 inhibitor that reduces pain and inflammation with less stomach irritation than traditional N...

Buprenorphine

Opioid1981

A partial opioid agonist that treats opioid addiction and chronic pain. Buprenorphine, sold with naloxone as S...

Atorvastatin

Statin1996

A statin medication that lowers LDL cholesterol by inhibiting HMG CoA reductase, the rate limiting enzyme in c...

Simvastatin

Statin1991

A statin derived from a fermentation product of Aspergillus terreus. Simvastatin or Zocor treats elevated chol...

Lisinopril

ACE Inhibitor1987

An ACE inhibitor that is one of the most prescribed medications in the US. Lisinopril treats high blood pressu...

Enalapril

ACE Inhibitor1981

An ACE inhibitor that was one of the first successful drugs in its class. Enalapril or Vasotec treats high blo...

Carvedilol

Beta Blocker1995

A third generation beta blocker that blocks both beta and alpha receptors. Carvedilol or Coreg treats heart fa...

Amlodipine

Calcium Channel Blocker1990

A calcium channel blocker and one of the most prescribed medications in the world. Amlodipine or Norvasc treat...

Nifedipine

Calcium Channel Blocker1981

A dihydropyridine calcium channel blocker used for high blood pressure and angina. Nifedipine was the first dr...

Losartan

ARB1995

The first angiotensin receptor blocker or ARB, developed by DuPont. Losartan treats high blood pressure and he...

Valsartan

ARB1996

An angiotensin receptor blocker that treats high blood pressure and heart failure. Valsartan or Diovan is also...

Clopidogrel

Antiplatelet1997

An antiplatelet medication that prevents blood clots in arteries. Clopidogrel or Plavix treats patients after ...

Metformin

Antidiabetic1995

The first line oral medication for type 2 diabetes. Metformin reduces glucose production in the liver and impr...

Glipizide

Sulfonylurea1984

A sulfonylurea that stimulates the pancreas to produce more insulin. Glipizide treats type 2 diabetes by closi...

Pioglitazone

Thiazolidinedione1999

An insulin sensitizer that activates PPAR gamma receptors. Pioglitazone or Actos treats type 2 diabetes by imp...

Acarbose

Alpha-glucosidase Inhibitor1990

A medication that delays carbohydrate absorption in the intestine. Acarbose treats type 2 diabetes by inhibiti...

Hepatitis B Vaccine

Vaccine1981

The first vaccine against a sexually transmitted infection and the first anti cancer vaccine, as hepatitis B c...

Acyclovir

Antiviral1982

One of the first selective antiviral drugs. Acyclovir treats herpes simplex virus infections including cold so...

Oseltamivir

Antiviral1999

An antiviral medication for influenza, better known as Tamiflu. Oseltamivir treats influenza A and B by inhibi...

Valacyclovir

Antiviral1995

A prodrug of acyclovir with much better oral absorption. Valacyclovir or Valtrex converts to acyclovir in the ...

Lamivudine

Antiviral1995

A nucleoside reverse transcriptase inhibitor used for both HIV and hepatitis B. Lamivudine or 3TC was one of t...

Fluoxetine

SSRI1987

One of the first SSRI antidepressants and the first to achieve wide success, marketed as Prozac. Fluoxetine re...

Sertraline

SSRI1991

An SSRI antidepressant marketed as Zoloft. Sertraline treats depression, anxiety disorders, PTSD, and OCD. It ...

Venlafaxine

SNRI1993

A serotonin norepinephrine reuptake inhibitor or SNRI. Venlafaxine or Effexor treats depression and anxiety di...

Bupropion

Antidepressant1985

An atypical antidepressant that inhibits dopamine and norepinephrine reuptake. Bupropion or Wellbutrin treats ...

Mirtazapine

Antidepressant1994

A tetracyclic antidepressant that enhances serotonin and norepinephrine activity. Mirtazapine or Remeron treat...

Alprazolam

Benzodiazepine1981

A short acting benzodiazepine marketed as Xanax. Alprazolam treats panic disorder and generalized anxiety. It ...

Quetiapine

Antipsychotic1997

An atypical antipsychotic marketed as Seroquel. Quetiapine treats schizophrenia, bipolar disorder, and is used...

Olanzapine

Antipsychotic1996

An atypical antipsychotic marketed as Zyprexa. Olanzapine treats schizophrenia and bipolar mania. It is highly...

Risperidone

Antipsychotic1993

An atypical antipsychotic marketed as Risperdal. Risperidone treats schizophrenia, bipolar disorder, and irrit...

Clozapine

Antipsychotic1989

The most effective antipsychotic for treatment resistant schizophrenia. Clozapine or Clozaril was the first at...

Omeprazole

Proton Pump Inhibitor1989

A proton pump inhibitor that dramatically reduces stomach acid production. Omeprazole or Prilosec was the firs...

Pantoprazole

Proton Pump Inhibitor1994

A proton pump inhibitor similar to omeprazole. Pantoprazole or Protonix treats GERD and stomach ulcers. It has...

Ranitidine

H2 Blocker1981

An H2 receptor blocker that was one of the most used medications in the world. Ranitidine or Zantac reduced st...

Famotidine

H2 Blocker1985

An H2 receptor blocker that replaced ranitidine after its withdrawal. Famotidine or Pepcid treats GERD and sto...

Ondansetron

Antiemetic1991

A 5 HT3 receptor antagonist that revolutionized nausea treatment. Ondansetron or Zofran prevents nausea and vo...

Mesalamine

Aminosalicylate1987

An anti inflammatory medication for inflammatory bowel disease. Mesalamine or Asacol treats ulcerative colitis...

Polyethylene Glycol

Laxative1999

An osmotic laxative marketed as MiraLAX. Polyethylene glycol treats constipation by drawing water into the int...

Albuterol

Bronchodilator1981

A short acting beta 2 agonist or SABA that quickly opens airways. Albuterol or Ventolin treats asthma attacks ...

Fluticasone

Corticosteroid1993

An inhaled corticosteroid that reduces airway inflammation. Fluticasone or Flovent treats asthma by preventing...

Montelukast

Leukotriene Receptor Antagonist1998

A leukotriene receptor antagonist taken as a tablet. Montelukast or Singulair treats asthma and allergic rhini...

Salmeterol

Bronchodilator1990

A long acting beta 2 agonist or LABA that provides 12 hour bronchodilation. Salmeterol or Serevent treats asth...

Ipratropium

Bronchodilator1986

A short acting anticholinergic bronchodilator. Ipratropium or Atrovent treats COPD and asthma by blocking musc...

Budesonide

Corticosteroid1981

An inhaled corticosteroid with excellent safety profile. Budesonide or Pulmicort treats asthma and inflammator...

Somatropin

Growth Hormone1985

Synthetic human growth hormone used to treat growth hormone deficiency in children and adults. Somatropin or G...

Loratadine

Antihistamine1993

A second generation antihistamine marketed as Claritin. Loratadine treats allergic rhinitis and hives without ...

Cetirizine

Antihistamine1987

A second generation antihistamine marketed as Zyrtec. Cetirizine treats allergic rhinitis, hives, and other al...

Fexofenadine

Antihistamine1996

A third generation antihistamine marketed as Allegra. Fexofenadine treats allergic rhinitis and hives with the...

Propofol

Anesthetic1986

An intravenous general anesthetic marketed as Diprivan. Propofol induces anesthesia rapidly with a smooth, ple...

Sevoflurane

Anesthetic1990

An inhaled anesthetic that is the most commonly used gas anesthetic in developed countries. Sevoflurane or Ult...

Midazolam

Sedative1982

A short acting benzodiazepine used for sedation before procedures. Midazolam or Versed causes sedation, anxiet...

Gabapentin

Anticonvulsant1993

A medication originally developed for seizures but now primarily used for nerve pain. Gabapentin or Neurontin ...

Lamotrigine

Anticonvulsant1994

An antiseizure medication also approved for bipolar disorder. Lamotrigine or Lamictal treats partial and gener...

Levetiracetam

Anticonvulsant1999

A widely used antiseizure medication marketed as Keppra. Levetiracetam treats partial and generalized seizures...

Topiramate

Anticonvulsant1996

An antiseizure medication also approved for migraine prevention. Topiramate or Topamax treats partial seizures...

Cyclosporine

Immunosuppressant1983

A calcineurin inhibitor that revolutionized organ transplantation. Cyclosporine or Sandimmune prevents organ r...

Tacrolimus

Immunosuppressant1994

A calcineurin inhibitor more potent than cyclosporine. Tacrolimus or Prograf prevents organ transplant rejecti...

Mycophenolate

Immunosuppressant1995

An immunosuppressant that inhibits purine synthesis in lymphocytes. Mycophenolate or CellCept prevents organ t...

Trastuzumab

Monoclonal Antibody1998

A monoclonal antibody targeting HER2 positive breast cancer. Trastuzumab or Herceptin treats the roughly 15 to...

Paclitaxel

Chemotherapy1992

A chemotherapy drug derived from the bark of the Pacific yew tree. Paclitaxel or Taxol treats breast, ovarian,...

Rituximab

Monoclonal Antibody1997

The first monoclonal antibody approved for cancer treatment. Rituximab or Rituxan targets CD20, a protein on B...

Latanoprost

Eye Pressure1996

A prostaglandin analog eye drop that lowers intraocular pressure. Latanoprost or Xalatan treats glaucoma, the ...

Minoxidil

Hair Growth1988

A medication originally developed for high blood pressure that was found to stimulate hair growth. Minoxidil o...

Isotretinoin

Retinoid1982

A powerful oral retinoid for severe cystic acne. Isotretinoin or Accutane treats nodular acne that has not res...

Sumatriptan

Triptan1991

The first triptan medication for acute migraine. Sumatriptan or Imitrex treats migraine headaches by stimulati...

Epoetin Alfa

Erythropoietin1989

A recombinant form of erythropoietin, the hormone that stimulates red blood cell production. Epoetin alfa or E...

Sildenafil

PDE5 Inhibitor1998

A medication originally developed for angina that became a blockbuster for erectile dysfunction. Sildenafil or...

Finasteride

5-Alpha Reductase Inhibitor1992

A medication that treats enlarged prostate and male pattern baldness. Finasteride or Proscar treats benign pro...

Enoxaparin

Anticoagulant1993

A low molecular weight heparin or LMWH. Enoxaparin or Lovenox prevents and treats blood clots. It replaced unf...

Praziquantel

Anthelmintic1982

A medication that treats schistosomiasis and other parasitic worm infections. Praziquantel is the primary trea...

Albendazole

Anthelmintic1982

A broad spectrum antiparasitic medication. Albendazole or Albenza treats roundworm, hookworm, whipworm, and ta...

Ivermectin

Anthelmintic1987

A medication developed from bacteria discovered by Satoshi Omura, who received the Nobel Prize in 2015. Iverme...

Piperacillin-Tazobactam

Antibiotic1993

A combination of a broad spectrum penicillin with a beta lactamase inhibitor. Piperacillin tazobactam or Zosyn...

Meropenem

Antibiotic1996

A broad spectrum carbapenem antibiotic reserved for the most serious infections. Meropenem treats hospital acq...

Ceftriaxone

Antibiotic1982

A third generation cephalosporin and one of the most used antibiotics in hospitals. Ceftriaxone or Rocephin tr...

Ketorolac

NSAID1989

A potent injectable NSAID used for short term management of moderate to severe acute pain. Ketorolac or Torado...

Nabumetone

NSAID1991

A non acid NSAID prodrug that is converted to its active form in the liver. Nabumetone or Relafen treats osteo...

Fenofibrate

Fibrate1998

A fibrate medication that lowers triglycerides and raises HDL cholesterol. Fenofibrate or Tricor treats hypert...

Ceftazidime

Antibiotic1985

A third generation cephalosporin with excellent activity against Pseudomonas aeruginosa. Ceftazidime or Fortaz...

Clavulanate

Beta-Lactamase Inhibitor1981

A beta lactamase inhibitor that is combined with amoxicillin as Augmentin. Clavulanic acid has no antibiotic a...

Sulbactam

Beta-Lactamase Inhibitor1986

A beta lactamase inhibitor combined with ampicillin as Unasyn. Sulbactam protects ampicillin from bacterial be...

Tazobactam

Beta-Lactamase Inhibitor1993

A beta lactamase inhibitor combined with piperacillin as Zosyn. Tazobactam protects piperacillin from bacteria...

Cefepime

Antibiotic1994

A fourth generation cephalosporin with broad spectrum activity. Cefepime or Maxipime treats hospital acquired ...

Aztreonam

Antibiotic1986

A monobactam antibiotic active only against gram negative bacteria. Aztreonam or Azactam treats infections cau...

Capecitabine

Chemotherapy1998

An oral chemotherapy prodrug that converts to fluorouracil in the body. Capecitabine or Xeloda treats breast c...

Gemcitabine

Chemotherapy1996

A chemotherapy drug used for some of the most difficult cancers. Gemcitabine or Gemzar treats pancreatic cance...

Cabergoline

Dopamine Agonist1996

A longer acting dopamine agonist preferred over bromocriptine for prolactinomas. Cabergoline or Dostinex treat...

Fluconazole

Antifungal1990

A triazole antifungal medication. Fluconazole or Diflucan treats yeast infections including vaginal candidiasi...

Terbinafine

Antifungal1991

An allylamine antifungal medication. Terbinafine or Lamisil treats fungal nail infections and ringworm. For na...